Opioid drugs like morphine and fentanyl are a mainstay of modern pain medicine. But they also cause constipation, are highly addictive, and can lead to fatal respiratory failure if taken at too high a dose. Scientists have ...
Biochemistry
Jun 22, 2018
0
74
One of the challenges of modern pharmacology is specificity. Despite therapeutic effects, drugs can often have side effects. The biological basis for this has to do with the proteins and receptors that the drug targets and ...
Biochemistry
Jun 18, 2018
0
84
For the first time, scientists have visualized the interaction between two critical components of the body's vast cellular communication network, a discovery that could lead to more effective medications with fewer side effects ...
Biochemistry
Jun 13, 2018
0
24
Using an informatics tool that identifies "hotspots" of post-translational modification (PTM) activity on proteins, researchers have found a previously-unknown mechanism that puts the brakes on an important cell signaling ...
Cell & Microbiology
May 7, 2018
0
74
T cells protect the body from foreign substances (known as antigens) and are an essential component of the body's immune system. New immunotherapies that use a patient's own T cells to treat disease have already proven strikingly ...
Bio & Medicine
Apr 30, 2018
0
34
A team of plant geneticists at Cold Spring Harbor Laboratory (CSHL) has identified a protein receptor on stem cells involved in plant development that can issue different instructions about how to grow depending on what peptide ...
Biotechnology
Mar 22, 2018
0
128
Plants lack eyes and ears, but they can still see, hear, smell and respond to environmental cues and dangers—especially to virulent pathogens. They do this with the aid of hundreds of membrane proteins that can sense microbes ...
Plants & Animals
Jan 19, 2018
0
1870
A new study reveals the molecular structure of a protein called alpha(α)Klotho, and how it helps to transmit a hormonal signal that slows aging.
Biochemistry
Jan 17, 2018
0
61
What if scientists could develop an opioid-based painkiller that is not addictive and has limited side effects?
Cell & Microbiology
Jan 5, 2018
49
4312
Researchers have engineered an artificial protein that may block malignant properties of cancer cells as well as correct certain birth defects.
Biochemistry
Nov 14, 2017
0
27
