Using a revolutionary live-cell microscopy technique, an international team of scientist has for the first time observed individual receptors for hormones and drugs working in intact cells.
Biochemistry
Oct 19, 2017
0
190
The ability to track the movements of single molecules has revealed how proteins on the surface of nerve cells control gates that turn chemical signals into electrical signals. The finding is a step forward in detailing mechanisms ...
Biochemistry
Oct 9, 2017
0
102
A powerful new way of analysing how drugs interact with molecules in the body could aid the design of better treatments with fewer side-effects.
Biochemistry
Oct 5, 2017
0
81
With the heightened concerns over the dangerous side effects of the once-popular antidiabetic drug Avandia, researchers at The Scripps Research Institute (TSRI) in Jupiter, Florida, are working to understand how small molecules, ...
Biochemistry
Sep 30, 2017
0
93
A team spearheaded by Van Andel Research Institute scientists has answered a long-standing question that may lead to more effective drugs with fewer side effects for diseases ranging from heart failure to cancer.
Biochemistry
Jul 27, 2017
0
94
Glutamate receptors play a central role in the human nervous system. Scientists estimate 90 percent of the human brain's synapses, or connections between neurons, send signals using glutamate. The role of similar receptors ...
Cell & Microbiology
Jul 24, 2017
0
11
As senses go, there's nothing so immediate and concrete as our sense of touch. So it may come as a surprise that, on the molecular level, our sense of touch is still poorly understood.
Cell & Microbiology
Jul 4, 2017
0
266
Researchers at the University of Michigan, Stanford University and biotech company ConfometRx have captured the first cryo-electron microscopy snapshots of a key cellular receptor in action.
Biochemistry
May 24, 2017
2
8
Opioids have long been an important tool in the world of pain management, but the side effects of these drugs - from addiction and respiratory failure to severe itching and dizziness, can be overwhelming. Scientists have ...
Biochemistry
Mar 27, 2017
0
9
A recent study published in Cell Chemical Biology has revealed new insights into a molecular pathway that leads to Staphylococcus aureus virulence. Using a tool that mimics the cellular environment, Princeton University researchers ...
Cell & Microbiology
Feb 7, 2017
0
13
