Human cells have a sophisticated regulatory system that consists of labeling proteins with the small molecule ubiquitin. In a first, a team from the Technical University of Munich (TUM) has succeeded in marking proteins with ...
Biochemistry
Apr 4, 2019
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14
A nanoscale antibody first found in camels combined with a protein-degrading molecule is an effective new platform to control protein levels in cells, according to Rice University scientists. The technique could aid fundamental ...
Cell & Microbiology
Oct 30, 2017
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99
New scientific techniques are revealing the intricate role that proteins play in photosynthesis.
Plants & Animals
Mar 11, 2021
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73
The latest developmental drugs, particularly for use in oncology, rely on the targeted degradation of harmful pathogenic proteins. In a recent study published in Nature Chemical Biology, researchers at CeMM, the Research ...
Biochemistry
Nov 3, 2022
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32
A research team from the Department of Chemistry at the Universität Hamburg has succeeded for the first time in identifying at the molecular level the dynamic mechanism used by the enzyme RNase R to degrade the ribosomal ...
Biochemistry
Feb 8, 2024
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5
Scientists at Yale University have described in the greatest detail yet aspects of the chemical processes by which RNA carries out the expression of our genes.
Cell & Microbiology
Oct 29, 2012
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0
(PhysOrg.com) -- Scientists from Imperial College London and Diamond Light Source have revealed the structure of a cholesterol-lowering-drug target. Published in the journal Nature, this finding could lead to much more effective ...
Biochemistry
Oct 6, 2011
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0
Messenger RNA (mRNA) levels dictate most differences protein levels in fast-growing cells when analyzed using statistical methods that account for noise in the data, according to a new study by researchers from the University ...
Cell & Microbiology
May 7, 2015
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23
New modeling shows how synonymous mutations—those that change the DNA sequence of a gene but not the sequence of the encoded protein—can still impact protein production and function. A team of researchers led by Penn ...
Biochemistry
Dec 5, 2022
0
15
A common activity in our daily household chores is separating paper, glass, cans, and plastic to deposit them in the appropriate containers. Through recycling, we can reduce resource consumption, save energy, and minimize ...
Cell & Microbiology
Jun 19, 2023
0
12
