A research team from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences / IOCB Prague has developed a novel computational method that can accurately describe how proteins interact with molecules ...
Analytical Chemistry
Feb 20, 2024
0
23
Researchers led by Northwestern University and the University of Wisconsin-Madison have introduced a pioneering approach aimed at combating neurodegenerative diseases such as Alzheimer's disease, Parkinson's disease and Amyotrophic ...
Bio & Medicine
Feb 18, 2024
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64
When researchers want to study how COVID makes us sick, or what diseases such as Alzheimer's do to the body, one approach is to look at what's happening inside individual cells. Researchers sometimes grow the cells in a 3D ...
Cell & Microbiology
Jan 31, 2024
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7
For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat surfaces or require ...
Biochemistry
Dec 28, 2023
0
203
Researchers at Kanazawa University report in the Journal of Physical Chemistry Letters high-speed atomic force microscopy studies that shed light on the possible role of the open reading frame 6 (ORF6) protein in COVID-19 ...
Biochemistry
Nov 29, 2023
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59
A detailed atomic exploration into how the dengue virus replicates its genome could catalyze the development of high-precision targeted antiviral therapeutics.
Cell & Microbiology
Oct 31, 2023
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1
The key to understanding proteins—such as those that govern cancer, COVID-19, and other diseases—is quite simple: Identify their chemical structure and find which other proteins can bind to them. But there's a catch.
Biotechnology
Aug 3, 2023
0
77
Protein dynamics through motions of loops, linkers, and hinges can generate distinctive conformations that are important for protein function. Most proteins perform their functions in cells. However, how the complex cellular ...
Cell & Microbiology
Jul 27, 2023
0
1
Researchers at IRB Barcelona, the University of Barcelona (UB), VIMM, and the University of Padua unveil the key role of Mitofusin 2 cellular makeup in interconnecting organelles within cells. The findings are published in ...
Cell & Microbiology
Jun 28, 2023
0
14
Fundamentally, life comes down to molecules contacting and binding to other molecules.
Cell & Microbiology
Jun 13, 2023
0
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