When the machinery that guides the transition of stem cells to somatic cells doesn't shut down properly, cells can become cancerous. Identifying the mechanisms that impede those processes would offer scientists a target for ...
Cell & Microbiology
Feb 11, 2020
0
111
To address the receptor dysfunction associated with several serious neurological diseases, Michaela Jansen, Pharm.D., Ph.D., from the Texas Tech University Health Sciences Center School of Medicine recently completed a study ...
Molecular & Computational biology
Feb 4, 2020
0
8
Researchers at Ben-Gurion University of the Negev (BGU) and The Hebrew University of Jerusalem (HU) have developed a powerful tool that will streamline and accelerate the development of disease therapies, transforming a multi-year ...
Biotechnology
Jan 22, 2020
2
114
Developing new medicines and understanding how they target specific organs often gives a crucial advantage in the fight against human diseases. An international team led by researchers at the European Molecular Biology Laboratory ...
Biotechnology
Jan 22, 2020
0
12
An iterative machine learning approach has identified elusive 800 million-year-old amino acid patterns that are responsible for facilitating protein interactions.
Molecular & Computational biology
Jan 6, 2020
0
7
Why do certain proteins in the body bind with some substances, but not with others?
Molecular & Computational biology
Dec 18, 2019
0
4
A team of researchers at Ehime University revealed that E3 ubiquitin ligase MIB2 enhances inflammation by degrading the deubiquitinating enzyme CYLD. This finding was published on Sept. 20 in the Journal of Biological Chemistry.
Molecular & Computational biology
Oct 29, 2019
0
4
"The strategy was to design the drug to be able to hook into the hole of the FTase and GGTase I, otherwise the surface of the proteins are too large and slippery," Dr. Junko Ohkanda of Shinshu University explains her strategy ...
Biochemistry
Sep 24, 2019
0
7
A hallmark of age-related diseases such as Parkinson's disease, type 2 diabetes, or Alzheimer's disease is the abnormal clumping of proteins in cells. In people with these conditions, these protein clumps can result in irregular ...
Biochemistry
Sep 16, 2019
0
25
Biologists at Columbia University Vagelos College of Physicians and Surgeons have leveraged a computational method to map protein-protein interactions between all known human-infecting viruses and the cells they infect. The ...
Cell & Microbiology
Aug 29, 2019
0
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