Fish and humans: A new approach to Bloom syndrome research

Researchers at Eötvös Loránd University (ELTE) have created a new disease model that has contributed to a better understanding of Bloom syndrome and the sex determination processes of zebrafish. The study, linking two ...

Malaria parasite's survival linked to two proteins

Malaria, a mosquito-borne disease, killed more than 620,000 people worldwide in 2020. Jeopardizing the survival of Plasmodium falciparum, the malaria parasite, is one way to control the spread of this deadly disease.

'Hotspot mapping' accelerates early-phase drug design

The amount of structural data on protein drug targets continues to grow. However, successfully mining this data to form testable hypotheses that drive drug discovery can prove challenging. Selectivity for the target protein ...

Dual brake on transport protein prevents cells from exploding

A high concentration of salt or sugar in the environment will dehydrate microorganisms and stop them from growing. To counter this, bacteria can increase their internal solute concentration. Scientists from the University ...

Condensins mutually interact to fold DNA into a zigzag structure

DNA in a cell is comparable to tangled spaghetti strands on a plate. To be able to divide DNA neatly between the two daughter cells during cell division, the cell organises this tangle into tightly packed chromosomes. A protein ...

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