Harnessing the moonseed plant's chemical know-how

In overgrown areas from Canada to China, a lush, woody vine with crescent-shaped seeds holds the secret to making a cancer-fighting chemical. Now, Whitehead Institute researchers in Member Jing-Ke Weng's lab have discovered ...

Nanopore reveals shape-shifting enzyme linked to catalysis

University of Groningen scientists have observed the characteristics of a single enzyme inside a nanopore. They learned that the enzyme can exist in four different folded states, or conformers, that play an active role in ...

How enzymes build sugar trees

Researchers have used cryo-electron microscopy to elucidate for the first time the structure and function of a very small enzyme embedded in cell membranes. This enzyme builds complex sugar trees that are subsequently attached ...

First artificial enzyme created with two non-biological groups

Scientists at the University of Groningen turned a non-enzymatic protein into a new, artificial enzyme by adding two abiological catalytic components: an unnatural amino acid and a catalytic copper complex. This is the first ...

Resurrected protein reveals structure of important enzyme

To disarm toxic substances, many organisms including humans possess enzymes called flavin-containing monooxygenases (FMOs). Despite their importance, the structure of the enzymes has not been resolved, as the protein is too ...

Organic packaging to protect enzymes

As soon as you take medication, your body is already working on removing it from your body. According to UT Ph.D. student Robin Klem, encapsulins—a kind of hollow protein ball—have the potential to protect enzymes and ...

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