Researchers from Facebook AI Research (FAIR) at Meta AI have published a paper in the journal Science detailing a machine-learning-created database of 617 million predicted protein structures. The ESMFold language model described ...
Human saliva may contain an enzyme which can decompose the plastic polyethylene terephthalate (PET). Researchers found the promising enzyme, a hydrolase, in a database containing human metagenome samples. As they report in ...
Biochemistry
Jun 29, 2022
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691
Researchers at MIT's McGovern Institute for Brain Research have discovered a bacterial enzyme that they say could expand scientists' CRISPR toolkit, making it easy to cut and edit RNA with the kind of precision that, until ...
Biotechnology
Sep 20, 2021
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472
Researchers at the University of Bristol have shown how laboratory evolution can give rise to highly efficient enzymes for new-to-nature reactions, opening the door for novel and more environmentally friendly ways to make ...
Biochemistry
Aug 19, 2021
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1056
For much of human history, animals and plants were perceived to follow a different set of rules than the rest of the universe. In the 18th and 19th centuries, this culminated in a belief that living organisms were infused ...
Molecular & Computational biology
Jul 22, 2021
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379
Builders of genetic circuits face the same quandary as builders of digital circuits: testing their designs. Yet unlike bioengineers, engineers have a simple and universal testing tool—the multimeter—that they can touch ...
Molecular & Computational biology
May 21, 2019
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104
Proteins fold according to a script written in the pattern of their amino acids. But to function properly, some parts must ad-lib.
Biochemistry
Feb 11, 2019
1
49
Protein engineers at the California Institute of Technology (Caltech) have tapped into a hidden talent of one of nature's most versatile catalysts. The enzyme cytochrome P450 is nature's premier oxidation catalyst—a protein ...
Materials Science
Dec 20, 2012
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0
Like a shadowy character just hidden from view, a mystery atom in the middle of a complex enzyme called nitrogenase had long hindered scientists' ability to study the enzyme fully.
Materials Science
Nov 17, 2011
1
0
Gamers have solved the structure of a retrovirus enzyme whose configuration had stumped scientists for more than a decade. The gamers achieved their discovery by playing Foldit, an online game that allows players to collaborate ...
Cell & Microbiology
Sep 18, 2011
3
0
