'Super' simulations offer fresh insight into serotonin receptors

Scientists at the University of Maryland (UMD) and the National Institute of Standards and Technology (NIST) have discovered a way to detect the molecular mechanism by which 5HT3A, a serotonin receptor located at the neuron ...

Faster modeling of interactions between ligands and proteins

A computational method for simulating the interaction between small molecules and proteins has been enhanced by an all-RIKEN team. This improvement promises to boost the speed and accuracy of designing new drugs.

Gene-OFF switches tool up synthetic biology

In the quest for tomorrow's diagnostics, therapeutics, and bioproduced drugs and fine chemicals, synthetic biologists are assembling artificial networks of genes and modular regulatory elements, similar to the electronic ...

The plus and minus of microtubules

Microtubules are protein polymers that assemble into dynamic structures, essential for cell division, shape, motility, and transport of intracellular cargos.

Scientists develop novel method to monitor molecular aggregation

Chiral molecules are defined as molecules that are non-superimposable on their mirror images, much like that of left and right human hand bone structure. There are many examples of chiral molecules in nature, including proteins ...

Novel probe for metabolic diseases

NUS pharmaceutical scientists have developed a simple, yet highly sensitive probe to detect the fat mass and obesity-associated protein (FTO) levels in cells. This can potentially help in the early detection and diagnosis ...

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