Proteins are constantly performing a kind of dance. They move and contort their bodies to fulfill specific functions inside our bodies. The NMDAR protein executes an especially hard dance routine in our brains.
Molecular & Computational biology
Jul 31, 2024
0
62
In a study published in PNAS, a research team has resolved the first high-resolution structure of the sgc8c DNA aptamer that targets protein tyrosine kinase 7 (PTK7), engineered two optimal sgc8c variants for disease theranostics ...
Molecular & Computational biology
Jul 19, 2024
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32
Effective pain relief without the debilitating side effects of traditional opioids is closer to becoming a reality thanks to a study by an all-RIKEN team into the structure and dynamics of a drug-bound opioid receptor.
Biotechnology
Jul 18, 2024
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99
Amyloids are protein aggregates that can form in the body, sometimes leading to diseases such as Alzheimer's. These fibrils can adopt multiple shapes, known as "polymorphs," which complicate our understanding of their role ...
Molecular & Computational biology
Jul 16, 2024
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0
A team led by Prof. Dr. Han Sun from the Leibniz-Forschungsinstitut für Molekulare Pharmakologie (FMP) has elucidated an important mechanism in the function of TREK channels at an atomic level. The results, published in ...
Molecular & Computational biology
Jul 10, 2024
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25
HIV, Ebola and most recently, COVID-19 viruses have had an enormous impact on our societies world-wide. All these viruses are "enveloped viruses," viruses that have an exterior envelope that surrounds them largely composed ...
Biochemistry
Jul 3, 2024
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21
Researchers at the University of Toronto have developed a deep-learning model, called PepFlow, that can predict all possible shapes of peptides—chains of amino acids that are shorter than proteins, but perform similar biological ...
Molecular & Computational biology
Jun 27, 2024
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10
A new AI-powered program will allow researchers to level up their drug discovery efforts.
Biotechnology
Jun 21, 2024
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56
Australian researchers, led by Monash University, have invented a new artificial intelligence (AI) tool which is poised to reshape virtual screening in early stage drug discovery and enhance scientists' ability to identify ...
Biochemistry
Jun 17, 2024
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31
A relatively simple peptide modification could unlock a whole class of targets for drug discovery, new research shows.
Analytical Chemistry
Jun 7, 2024
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0
