Just like a doctor adjusts the dose of a medication to the patient's needs, the expression of therapeutic genes, those modified in a person to treat or cure a disease via gene therapy, also needs to be maintained within a ...
Biotechnology
Jan 2, 2024
0
155
For decades, a substantial number of proteins, vital for treating various diseases, have remained elusive to oral drug therapy. Traditional small molecules often struggle to bind to proteins with flat surfaces or require ...
Biochemistry
Dec 28, 2023
0
203
p38α protein, a key enzyme in the regulation of various cellular functions, plays a crucial role in some diseases, including cancer, chronic inflammation, and neurodegenerative conditions. Since the discovery of p38α, various ...
Cell & Microbiology
Dec 19, 2023
0
1
A new study in Nature reports an AI-driven advance in biotechnology with implications for drug development, disease detection, and environmental monitoring. Scientists at the Institute for Protein Design at the University ...
Biotechnology
Dec 18, 2023
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85
Neurotransmitters are a class of signaling chemicals, including monoamines such as serotonin, dopamine, and histamine, which play a vital role in a variety of neurological activities, including mood, memory, growth and development, ...
Biotechnology
Dec 15, 2023
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17
Most diseases are caused by proteins that have spun out of control. Unfortunately, so far, conventional drugs have been able to stop only a fraction of these troublemakers. A new class of drugs known as PROTACs holds great ...
Biochemistry
Dec 11, 2023
0
57
The field of epigenetics focuses on alterations in gene function that are inherited without changes in the DNA sequence, including histone modifications, post-translational modifications of amino acids, and covalent modifications ...
Molecular & Computational biology
Dec 6, 2023
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2
Exploring the biomedical interactions for chemical compounds and protein targets is crucial for drug discovery. Determining these drug–drug interactions (DDI) and drug–target interactions (DTI) not only reveals the potential ...
Molecular & Computational biology
Dec 5, 2023
0
23
While we often think of diseases as caused by foreign bodies—bacteria or viruses—there are hundreds of diseases affecting humans that result from errors in cellular production of proteins.
Cell & Microbiology
Dec 4, 2023
0
323
Scientists at the University of Bath have used nature as inspiration in developing a new tool that will help researchers develop new pharmaceutical treatments in a cleaner, greener, and less expensive way.
Biochemistry
Nov 28, 2023
0
42
