Popular new construction material helps measure protein particles

Understanding how proteins clump together is essential in modern pharmaceuticals. When these tiny particles aggregate, they can alter the effectiveness of both vaccines and drugs, especially many of the new, popular formulations ...

Directed evolution builds nanoparticles

The 2018 Nobel Prize in Chemistry went to three scientists who developed the method that forever changed protein engineering: directed evolution. Mimicking natural evolution, directed evolution guides the synthesis of proteins ...

Mega docking library poised to speed drug discovery

Researchers have launched an ultra-large virtual docking library expected to grow to more than 1 billion molecules by next year. It will expand by 1000-fold the number of such "make-on-demand" compounds readily available ...

Nanoparticle breakthrough in the fight against cancer

A recent study, affiliated with South Korea's Ulsan National Institute of Science and Technology (UNIST) has introduced a novel targeted drug delivery system in the fight against cancer.

Seeing small-molecule interactions inside cells

Like people in a large company, proteins in cells constantly interact with each other to perform various jobs. To develop new disease therapies, researchers are trying to control these interactions with small-molecule drugs ...

Researchers image atomic structure of important immune regulator

A new study by investigators from Brigham and Women's Hospital provides a biophysical and structural assessment of a critical immune regulating protein called human T-cell immunoglobulin and mucin domain containing protein-3 ...

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