(Phys.org)—A team of researchers at MIT has found a way to modify proteins using palladium reagents, allowing for the possible creation of a host of therapeutic drugs. In their paper published in the journal Nature, the ...
Most pharmaceutical drugs consist of tiny molecules, which target a class of proteins found on the surfaces of cell membranes. Studying these subtle interactions is essential for the design of effective drugs, but the task ...
Biochemistry
Oct 23, 2015
0
920
Many of the drugs we take today to treat pain, fight cancer or thwart disease were originally identified in plants, some of which are endangered or hard to grow. In many cases, those plants are still the primary source of ...
Biochemistry
Sep 10, 2015
2
4633
The first three-dimensional image capturing a critical malaria 'conductor' protein could lead to the development of a new class of antimalarial drugs.
Cell & Microbiology
Jul 27, 2015
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34
A new study led by University of Kentucky researchers suggests a new approach to develop highly-potent drugs which could overcome current shortcomings of low drug efficacy and multi-drug resistance in the treatment of cancer ...
Bio & Medicine
Jul 7, 2015
0
27
Scientists have pioneered the use of a high-powered imaging technique to picture in exquisite detail one of the central proteins of life – a cellular recycling unit with a role in many diseases.
Biochemistry
Jul 2, 2015
0
1479
Current drugs block the actions of only about a quarter of known disease-causing proteins, but Yale University researchers have developed a technology capable of not just inhibiting, but destroying every protein it targets.
Biochemistry
Jun 11, 2015
0
86
Biochemists from Trinity College Dublin have devised a new technique that will make the difficult but critical job of blueprinting certain proteins considerably faster, easier and cheaper.
Biochemistry
Jun 5, 2015
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52
Scientists have discovered an extraordinary protein-cutting enzyme that has also evolved to glue proteins together, a finding that may be valuable in the production of therapeutic drugs.
Biochemistry
May 8, 2015
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39
A new study shows that it is possible to use an imaging technique called cryo-electron microscopy (cryo-EM) to view, in near-atomic detail, the architecture of a metabolic enzyme bound to a drug that blocks its activity. ...
General Physics
May 7, 2015
0
56
