From a drug perspective, G protein-coupled receptors are the most utilised cell receptors in the body. They are uniquely accessible at the cell surface, and a third of all drugs sold in the US target them.
Biochemistry
Oct 31, 2017
0
3
An artificial system using a DNA-laced hydrogel can receive a chemical signal and release the appropriate protein, according to Penn State researchers. Further stimulation by the chemical signal continues to trigger a response.
Biochemistry
Oct 26, 2017
0
9
Most drugs work by tinkering with the behavior of proteins. Like meddlesome coworkers, these molecules are designed to latch onto their target proteins and keep them from doing what they need to do.
Biochemistry
Oct 11, 2017
0
59
A powerful new way of analysing how drugs interact with molecules in the body could aid the design of better treatments with fewer side-effects.
Biochemistry
Oct 5, 2017
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81
Proteins and drugs are often attached to lipids to promote crystallization or ensure delivery to targeted tissues within the body, but only the smallest proteins and molecules fit within these fat structures. A new study ...
Biochemistry
Oct 2, 2017
0
97
With the heightened concerns over the dangerous side effects of the once-popular antidiabetic drug Avandia, researchers at The Scripps Research Institute (TSRI) in Jupiter, Florida, are working to understand how small molecules, ...
Biochemistry
Sep 30, 2017
0
93
Scientists have created a high-speed method to generate thousands of different, small, stable proteins from scratch that can be custom-designed to bind to specific therapeutic targets.
Biochemistry
Sep 27, 2017
0
331
A new test to show the properties of biologically important enzymes could help to streamline development of new treatments.
Biochemistry
Aug 17, 2017
0
107
University of Michigan biophysicists and chemists have created a new polymer that mimics a cell membrane, allowing proteins found within cell membranes to fold and function naturally in the synthetic material.
Cell & Microbiology
Aug 16, 2017
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5
Clinicians today have an arsenal of more than 200 drugs at their disposal for treating a range of cancers—68 drugs were approved between 2011 and 2016 alone. But many chemotherapeutic agents pose stubborn challenges: they ...
Materials Science
Aug 9, 2017
0
28
