From molecule to medicine via machine learning

It typically takes many years of experiments to develop a new medicine. Although vaccines to protect against disease from the novel coronavirus are starting to reach clinics around the world, patients and doctors will still ...

Undruggable diseases gain a new RNA drug-discovery tool

Imagine trying to throw a bullseye when the dartboard lies buried within a crumpled box. That's the challenge faced by scientists working to make new medicines for some 'undruggable' diseases, including a type of metastatic ...

Sugar-coated viral proteins hijack and hitch a ride out of cells

Researchers from the Universities of Melbourne, York, Warwick and Oxford have shed light on how encapsulated viruses like hepatitis B, dengue and SARS-CoV-2 hijack the protein manufacturing and distribution pathways in the ...

New understanding of how proteins operate

A ground-breaking discovery by Centenary Institute scientists has provided new understanding as to the nature of proteins and how they exist and operate in the human body.

New analysis method can lead to better cancer drugs

While proteins on the surfaces of cells are the targets for most drugs, refined methods are needed to analyze how these membrane proteins are organized. Researchers at Karolinska Institutet have developed a new DNA-based ...

Computer vision helps find binding sites in drug targets

Scientists from the iMolecule group at Skoltech Center for Computational and Data-Intensive Science and Engineering (CDISE) developed BiteNet, a machine learning (ML) algorithm that helps find drug binding sites, i.e. potential ...

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