On 08 March 2022, the journal BioDesign Research published a review article titled "What Have We Learned from Design of Function in Large Proteins?" by Olga Khersonsky and Sarel J. Fleishman. The article proposes an evolution-guided ...
Molecular & Computational biology
Apr 6, 2022
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7
A Duke University-led team has brought powerful software to the never-ending arms race between antibiotics and germs. Working together, computer scientists and biochemists have developed and laboratory-tested a computer program ...
Feb 16, 2009
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Researchers have developed a process that could sharply reduce the work involved in computational protein design, according to a study in Proceedings of the National Academy of Sciences.
Biochemistry
Feb 27, 2020
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203
Protein design is a popular and rapidly growing field, with scientists engineering novel protein cages—capsule-like nanostructures for purposes such as gene therapy and targeted drug delivery. Many of these structures fashioned ...
Biochemistry
Jan 23, 2020
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210
Transmembrane β-barrel pores (TMBs) are extensively used for single-molecule DNA and RNA sequencing. They enable the miniaturization of a wide array of sensing and sequencing applications into portable USB-size devices and ...
Bio & Medicine
Jul 18, 2024
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103
EPFL scientists have developed a computational method modeling and designing protein allostery that allows the accurate and rational engineering and even repurposing of cell receptors. The method can be a significant tool ...
Biochemistry
Dec 2, 2019
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36
A multidisciplinary team of mathematicians, theoretical physicists, chemists and biochemists from the University of Bristol came together to study the self-assembly of protein building into protein cages with possible applications ...
Biochemistry
Aug 7, 2017
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19
A new technology that uses a protein's structure to predict the inner wiring that controls the protein's function and dynamics is now available for scientists to utilize. The tool, developed by researchers at Penn State, ...
Biotechnology
Sep 3, 2020
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35
Proteins have now been designed in the lab to zip together in much the same way that DNA molecules zip up to form a double helix. The technique, whose development was led by University of Washington School of Medicine scientists, ...
Biochemistry
Dec 19, 2018
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108
Scientists have successfully applied reinforcement learning to a challenge in molecular biology. The team of researchers developed powerful new protein design software adapted from a strategy proven adept at board games like ...
Biotechnology
Apr 20, 2023
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