MicroRNAs (miRNAs) are short noncoding regulatory RNAs that can repress gene expression post-transcriptionally and are therefore increasingly used as biomarkers of disease. Detecting miRNAs can be arduous and expensive as ...
Evolving strains of multi-drug resistant pathogens are a growing global concern, outpacing drug discovery efforts and undermining the efficacy of existing antibiotics. The development of comprehensive diagnostics for clinical ...
(Phys.org) —A key feature of certain chemicals is their ability to bind to other molecules – a property that emerged through evolution – but current chemical theory lacks the ability to design binders from first principles. ...
(PhysOrg.com) -- Nobody knows quite how life originated on Earth, but most scientists agree that living cells did not abruptly appear from nonliving cells in a single step. Instead, there were probably a series of pre-cellular ...
(PhysOrg.com) -- With its unique double-helical structure, DNA has the ability to be used as a programmable building material to construct designer nanoscale architectures. Complex DNA architectures could have a variety of ...
Optothermal nanotweezers are an innovative optical design method that has revolutionized classical optical techniques to capture a broad range of nanoparticles. While the optothermal temperature field can be employed for ...
A simple statistical test shows that contrary to current practice, the "gaps" within DNA protein and sequence alignments commonly used in evolutionary biology can provide important information about nucleotide and amino acid ...
Evolution
Aug 16, 2022
3
591
New North Carolina State University research shows progress in gathering information on an important—yet difficult to characterize—human gut bacterium called Bifidobacterium, which is used in many probiotics that help ...
Cell & Microbiology
Jul 18, 2022
0
90
Johns Hopkins scientists have developed a streamlined method and accompanying efficiency "rules" for introducing new DNA sequences into cells after using the gene-cutting tool known as CRISPR. The scientists say the method, ...
Biotechnology
Dec 1, 2017
0
40
Day in and day out, in our bodies, the DNA in cells is damaged for a variety of reasons, and thus intercellular DNA-repair systems are fundamental to the maintenance of life. Now scientists from the UNC School of Medicine ...
Cell & Microbiology
Feb 7, 2017
0
1771
Nucleotides are molecules that, when joined together, make up the structural units of RNA and DNA. In addition, nucleotides participate in cellular signaling (cGMP and cAMP), and are incorporated into important cofactors of enzymatic reactions (coenzyme A, FAD, FMN, and NADP+). Nucleotide derivatives such as the nucleoside triphosphates play central roles in metabolism, in which capacity they serve as sources of chemical energy (ATP and GTP).
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