In organisms whose cells have a nucleus, like plants and animals, the basic packaging units of DNA are the so-called nucleosomes. A nucleosome consists of a segment of DNA wound around eight proteins known as histones. Gene ...
Bio & Medicine
Mar 6, 2023
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Scientists in Canada and the United States have used three-dimensional imaging techniques to settle a long-standing debate about how DNA and structural proteins are packaged into chromatin fibres. The researchers, whose findings ...
Biotechnology
Oct 4, 2012
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A novel technique has been developed and demonstrated at Penn State University to map the proteins that read and regulate chromosomes -- the string-like structures inside cells that carry genes. The specific order in which ...
Cell & Microbiology
Jan 18, 2012
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Plants are incredibly temperature sensitive and can perceive changes of as little as one degree Celsius. Now, a report in the January 8th issue of the journal Cell, a Cell Press publication, shows how they not only 'feel' ...
Cell & Microbiology
Jan 7, 2010
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The tight wrapping of genomic DNA around nucleosomes in the cell nucleus makes it unavailable for gene expression. A team of Ludwig-Maximilians-Universitaet (LMU) in Munich now describes a mechanism that allows chromosomal ...
Biochemistry
May 23, 2013
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One feature of cell division has long puzzled scientists. The nucleus briefly disappears, leaving the cell's DNA exposed. Normally, bare DNA indicates a viral infection and triggers enzymatic alarms that alert the immune ...
Cell & Microbiology
Sep 15, 2020
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78
Like thread tightly wrapped around a spool, DNA is wrapped around histones and packaged into structures called nucleosomes. Scientists at St. Jude Children's Research Hospital are exploring how a type of transcription factor ...
Cell & Microbiology
May 24, 2023
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137
LMU researchers have, for the first time, systematically determined the positioning of the packing units of the fruit fly genome and discovered a new protein that defines their relationship to the DNA sequence.
Plants & Animals
Nov 5, 2018
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11
Two scientists at the Johns Hopkins University School of Medicine have unraveled aspects of how DNA organizes and preserves genetic information. Newly published research by Cynthia Wolberger, Ph.D., and James Berger, Ph.D., ...
Molecular & Computational biology
May 22, 2019
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6
A protein complex called facilitates chromatin transcription (FACT) plays a role in DNA packing within a nucleus, as well as in oncogenesis. A team of scientists from MSU, working in cooperation with foreign colleagues, have ...
Cell & Microbiology
May 28, 2018
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