News tagged with nucleosomes

Slip-sliding away…

In the cell nucleus, the genomic DNA is packaged into a tightly condensed form, which is referred to as chromatin. The basic unit of chromatin organization is the nucleosome, a DNA-protein complex consisting of a defined ...

dateSep 04, 2018 in Cell & Microbiology
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Finding the proteins that unpack DNA

A new method allows researchers to systematically identify specialized proteins that unpack DNA inside the nucleus of a cell, making the usually dense DNA more accessible for gene expression and other functions. The method, ...

dateJul 12, 2018 in Cell & Microbiology
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A new, dynamic view of chromatin movements

In cells, proteins tightly package the long thread of DNA into pearl necklace-like complexes known as chromatin. Scientists at EPFL show for the first time how chromatin moves, answering longstanding questions about how its ...

dateJan 18, 2018 in Cell & Microbiology
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Which sequences make DNA unwrap and breathe?

Accessing DNA wrapped into basic units of packaging, called nucleosomes, depends on the underlying sequence of DNA building blocks, or base pairs. Like Christmas presents, some nucleosomes are easier to unwrap than others. ...

dateDec 05, 2017 in Biotechnology
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