Mycobacterium tuberculosis, the causative agent of tuberculosis, remains the leading cause of infectious disease worldwide, affecting approximately a quarter of the globe's population. Treatment of infections is problematic ...
Biochemistry
Jul 21, 2022
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83
(Phys.org)—A small team of researchers with the University of New South Wales and Monash University, both in Australia, has developed a theory that suggests tuberculosis may have evolved into a disease as a result of the ...
A new study, led by Qingyun Liu, Ph.D., assistant professor in the Department of Genetics, has uncovered a genetic feature known as "transcriptional plasticity," which plays a pivotal role in governing the transcriptional ...
Cell & Microbiology
Apr 18, 2024
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9
The bacterium behind tuberculosis is a wily foe, adept at bobbing and weaving around the immune system and antibiotics alike. Mycobacterium tuberculosis (Mtb) has been notoriously difficult to eradicate, often dormant in ...
Cell & Microbiology
Mar 20, 2024
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1
Researchers at the Francis Crick Institute have found that the body's process of removing old and damaged cell parts is also an essential part of tackling infections that take hold within our cells, like TB.
Cell & Microbiology
Mar 23, 2023
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38
As we now know from our experience with the COVID-19 pandemic, the microbes responsible for some infections can rapidly mutate into variants that evade detection and treatment.
Biochemistry
Feb 15, 2023
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36
One of the major obstacles that those conducting research on carbohydrates are constantly working to overcome is the limited array of tools available to decipher the role of sugars. As a workaround, most researchers utilize ...
Biochemistry
Dec 22, 2022
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66
Researchers have designed and synthesized analogs of a new antibiotic that is effective against multidrug-resistant bacteria, opening a new front in the fight against these infections.
Cell & Microbiology
Dec 20, 2022
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53
Researchers have developed a novel genome assembly tool that could spur the development of new treatments for tuberculosis and other bacterial infections.
Cell & Microbiology
Dec 16, 2022
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22
Hung-Jen Wu, associate professor in the Artie McFerrin Department of Chemical Engineering at Texas A&M University, is working to defeat bacteria that have become resistant to multiple types of antibiotics. To achieve interdisciplinary ...
Biochemistry
Nov 4, 2022
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122
Mycobacterium tuberculosis (MTB) is a pathogenic bacterial species in the genus Mycobacterium and the causative agent of most cases of tuberculosis. First discovered in 1882 by Robert Koch, M. tuberculosis has an unusual, waxy coating on the cell surface (primarily mycolic acid), which makes the cells impervious to Gram staining; acid-fast techniques are used instead. The physiology of M. tuberculosis is highly aerobic and requires high levels of oxygen. Primarily a pathogen of the mammalian respiratory system, MTB infects the lungs, causing tuberculosis.
The M. tuberculosis genome was sequenced in 1998.
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