Reducing naturally occurring errors in protein synthesis (production) improves both health and lifespan, finds a new study in simple model organisms led by researchers at UCL and MRC London Institute of Medical Sciences.
Cell & Microbiology
Sep 14, 2021
0
262
Despite remarkable medical advances over the last years, cystic fibrosis remains the most prevalent lethal genetic disease. It is due to mutations in the CFTR protein which is normally required to maintain proper fluid balances ...
Biochemistry
Aug 3, 2021
0
359
A team of researchers working at the Francis Crick Institute has developed a way to find mutations in similar genome regions of cancer samples. In their paper published in the journal Nature Biotechnology, the group describes ...
One of the key mutations seen in the 'Alpha variant' of SARS-CoV-2—the deletion of two amino acids, H69/V70—enables the virus to overcome chinks in its armour as it evolves, say an international team of scientists.
Cell & Microbiology
Jun 29, 2021
1
39
SARS-CoV-2 has evolved to acquire mutations on the spike protein—the part of the virus that protrudes from its surface and latches onto cells to infect them—that enhance the coronavirus' ability to bind to human cells ...
Biotechnology
May 19, 2021
0
126
Using a specialized protein, all bacteria are capable of rapidly and effectively repairing damage to their DNA from UV. However, this mutation frequency decline (Mfd) protein plays another role and causes mutations. A team1 ...
Cell & Microbiology
Apr 7, 2021
0
139
A warmer global climate can cause mutations to have more severe consequences for the health of organisms through their detrimental effect on protein function. This may have major repercussions on organisms' ability to adapt ...
Ecology
Feb 2, 2021
5
415
Exposure to mutagens, or mutation-causing agents, can not only bring about changes in DNA but also appear to induce errors when genes are transcribed to make proteins, which may be an important factor in age-related diseases.
Biotechnology
Dec 21, 2020
0
41
It might look like a little game at the molecular scale.
Molecular & Computational biology
Oct 14, 2020
0
190
A novel machine learning model developed by researchers at Michigan State University suggests that mutations to the SARS-CoV-2 genome have made the virus more infectious.
Molecular & Computational biology
Aug 20, 2020
1
3215
