A histone modifier that facilitates an epigenetic switch
Epigenetic regulation of gene expression is associated with switching between chromatin states characterized by distinct histone modifications.
Epigenetic regulation of gene expression is associated with switching between chromatin states characterized by distinct histone modifications.
Cell & Microbiology
Jun 30, 2020
0
120
Researchers in Germany identified the precise structural differences that determine if a protein becomes an active enzyme or an iron scaffold. This finding, reported in Nature Communications, provides deeper insight into ...
Cell & Microbiology
Apr 22, 2020
0
38
Quantitative biologists David McCandlish and Juannan Zhou at Cold Spring Harbor Laboratory have developed an algorithm with predictive power, giving scientists the ability to see how specific genetic mutations can combine ...
Biotechnology
Apr 14, 2020
1
991
To this end, the team identified several thousand proteins, determined their respective amounts in mutant and reference lines and combined the findings with measurements of photosynthetic performance. Their findings were ...
Plants & Animals
Apr 8, 2020
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20
Proteins, the workhorse of the human cell, help digest our food, carry oxygen through the body, fight off invading microbes, and so much moreābut they only function when folded properly into specific, three dimensional ...
Molecular & Computational biology
Mar 2, 2020
1
134
A research team led by scientists at the Whitehead Institute has described the structure of a key protein complex that helps activate mTORC1, a master growth regulator that enables cells to quickly respond to changing nutrient ...
Cell & Microbiology
Nov 6, 2019
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73
Myosins are motor proteins that convert chemical energy into mechanical work, generating force and movement. Myosin II generates forces that are essential to drive cell movements and cell shape changes that generate tissue ...
Biotechnology
Oct 28, 2019
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106
Researchers from the Stowers Institute for Medical Research have discovered a new function of ribosomes in human cells that may show the protein-making particle's role in destroying healthy mRNAs, the messages that decode ...
Molecular & Computational biology
May 24, 2019
1
420
Environmental conditions, lifestyle choices, chemical exposure, and foodborne and airborne pathogens are among the external factors that can cause disease. In contrast, internal genetic factors can be responsible for the ...
Molecular & Computational biology
May 21, 2019
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171
Nonsense mutations are single-letter errors in the genetic code that prematurely halt the production of critical proteins. These unfinished proteins are unable to function normally, and nonsense mutations cause 10-15 percent ...
Molecular & Computational biology
Feb 19, 2019
0
45