Scientists have identified a new role for a protein complex at the center of a human genetic disorder called Bardet-Biedl syndrome, or BBS, for which there is currently no cure.
Cell & Microbiology
May 31, 2022
0
42
When genes mutate, this can lead to severe diseases of the human nervous system. Researchers at Leipzig University and the University of Würzburg have now used fruit flies to demonstrate how, apart from the negative effect, ...
Other
May 10, 2022
0
399
Scientists at Emory have revealed widespread distortions of a cell's protein interaction machinery resulting from cancer-causing mutations. They developed a process resembling ground-penetrating radar, for its ability to ...
Cell & Microbiology
May 4, 2022
0
77
UT Southwestern researchers have identified a four-protein complex that appears to play a key role in generating ribosomes—organelles that serve as protein factories for cells—as well as a surprising part in neurodevelopmental ...
Cell & Microbiology
Mar 29, 2022
0
99
Scientists have obtained the first high-resolution 3D image of nebulin, a giant actin-binding protein that is an essential component of skeletal muscle. This discovery has brought to light the chance to better understand ...
Biotechnology
Feb 18, 2022
1
125
A mutated protein causes the genetic disease cystic fibrosis. Now, researchers have solved the structure of the protein and how certain drugs bind to it, unveiling their mode of action.
Cell & Microbiology
Jan 7, 2022
0
590
Each one of the trillions of cells that make up the human body suffers more than 10,000 DNA lesions every day. These injuries would be catastrophic if cells were unable to repair them, but a very delicate machinery that detects ...
Cell & Microbiology
Dec 28, 2021
0
254
For the first time, researchers have constructed a detailed 3D structure of human SAGA, a 20-piece molecular machine crucial to human life.
Molecular & Computational biology
Nov 23, 2021
0
50
A recent statistical study has revealed some of the constraints and directions in the evolution of the structure and function of proteins. Better models of protein structural dynamics may allow researchers to understand more ...
General Physics
Oct 14, 2021
0
93
Biologists at Cold Spring Harbor Laboratory (CSHL) are using a mathematical approach developed in CSHL Assistant Professor David McCandlish's lab to find solutions to a diverse set of biological problems. Originally created ...
Molecular & Computational biology
Oct 4, 2021
0
83
