The latest developmental drugs, particularly for use in oncology, rely on the targeted degradation of harmful pathogenic proteins. In a recent study published in Nature Chemical Biology, researchers at CeMM, the Research ...
Biochemistry
Nov 3, 2022
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32
Mitochondria—the organelles responsible for energy production in human cells—were once free-living organisms that found their way into early eukaryotic cells over a billion years ago. Since then, they have merged seamlessly ...
Cell & Microbiology
Oct 20, 2022
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69
About 15 years ago, a group of researchers discovered mutant zebrafish. The eyes of these zebrafish did not develop correctly, resulting in significantly smaller eyes than those of wild zebrafish. Now, one of these researchers—Prof. ...
Cell & Microbiology
Aug 9, 2022
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68
Insulin-like growth factor (IGF) is a hormone that greatly influences growth in fetuses and children, but also body maintenance and metabolism in adults. IGF regulates cell proliferation, differentiation, and survival by ...
Cell & Microbiology
Aug 9, 2022
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8
Researchers from the National Institutes of Health have developed a three-dimensional structure that allows them to see how and where disease mutations on the twinkle protein can lead to mitochondrial diseases. The protein ...
Molecular & Computational biology
Aug 5, 2022
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80
A team led by biologists at The University of Texas at Arlington has published a study supporting the theory that species that reproduce asexually have more harmful genetic mutations than those utilizing sexual reproduction.
Evolution
Aug 1, 2022
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218
Thanks to advances in genomics in recent decades, researchers now know the genetic mutations responsible for many diseases. However, researchers often still do not know how the mutation leads to the disease—what it changes ...
Cell & Microbiology
Jul 11, 2022
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500
When the coronavirus causing COVID-19 infects human cells, the cell's protein-processing machinery makes modifications to the spike protein that render it more flexible and mobile, which could increase its ability to infect ...
Cell & Microbiology
Jul 5, 2022
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274
In biology, getting rid of stuff can be just as important as making it. A buildup of cells, proteins, or other molecules that are no longer needed can cause problems, so living things have evolved several ways to clean house.
Biotechnology
Jun 9, 2022
0
65
In the prelude to cancer, genetic mutations can sometimes lead to the formation of chimeric proteins made from parts of two different proteins that are usually separate.
Cell & Microbiology
Jun 9, 2022
0
32
