Team develops psoriasis drug

Ben-Gurion University of the Negev (BGU) researchers, in collaboration with Teva Pharmaceutical Industries Ltd., have developed a promising drug candidate to treat psoriasis. The finding was reported in a new paper published ...

Hereditary neurodegeneration linked to ADP-ribose modification

Attaching chains of the small molecule ADP-ribose to proteins is important for a cell's survival and the repair of DNA damage, making this process a promising target for the development of new cancer drugs. Researchers have ...

The genetics of molecular evolution

A team of scientists researching the effect of long-term molecular evolution (the study of DNA, RNA and proteins) have produced findings which suggest most amino-acid substitutions have different fitness effects in different ...

Aggregation of proteins in cells may result in diseases

Changes in the structure of proteins can lead to various diseases, such as Alzheimer's, type 2 diabetes and corneal dystrophy. A research team from Aarhus University has now discovered how a particular protein can damage ...

Insights into primate diversity: Lessons from the rhesus macaque

New research published in BMC Genetics shows that the rhesus macaque has three times as much genetic variation than humans. However despite much of this extra variation being within genes, it does not affect protein function. ...

Defect in transport system causes DNA chaos in red blood cells

Within all our cells lies two meters of DNA, highly ordered in a structure of less than 10 micro meters in diameter. Special proteins called histones act as small building bricks, organising our DNA in this structure. Preservation ...

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