New CRISPR method efficiently corrects DMD defect in heart tissue

Scientists have developed a CRISPR gene-editing technique that can potentially correct a majority of the 3,000 mutations that cause Duchenne muscular dystrophy (DMD) by making a single cut at strategic points along the patient's ...

What a rare blood disease can teach us about blood clotting

When a person is injured, blood clotting is essential. However, once the danger has passed, it is equally essential to stop the clotting response in order to prevent thrombosis, or the obstruction of blood flow by clots. ...

A mutation giving leaves with white spots has been identified

Garden and potted plants with white spots on their leaves are so popular that they are specially selected for this feature. An international research team has now identified a new mutation in the plant Lotus japonicus which ...

New mechanism to fight multi-resistant bacteria revealed

In recent years, scientists, clinicians and pharmaceutical companies have struggled to find new antibiotics or alternative strategies against multi-drug resistant bacteria that represent a serious public health problem. In ...

Big data approach to predict protein structure

Nothing works without proteins in the body, they are the molecular all-rounders in our cells. If they do not work properly, severe diseases, such as Alzheimer's, may result. To develop methods to repair malfunctioning proteins, ...

Evolution silences harmful mutations

Sometimes so-called synonymous mutations occur in DNA. These do not lead to a change in the protein sequence but which may still have major negative effects on the ability of bacteria to survive. New research from Uppsala ...

New 3-D method improves the study of proteins

Researchers have developed a new computational method called AGGRESCAN3D which will allow studying the 3D structure of folded globular proteins and substantially improve the prediction of any propensity for forming toxic ...

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