An evolutionary breakpoint in cell division

Japanese researchers from Osaka University have discovered that the interaction between two proteins, M18BP1/KNL2 and CENP-A, is essential for cell division in various species except for mammals including human.

Highly efficient CRISPR knock-in in mouse

Genome editing using CRISPR/Cas system has enabled direct modification of the mouse genome in fertilized mouse eggs, leading to rapid, convenient, and efficient one-step production of knockout mice without embryonic stem ...

Learning the alphabet of gene control

Scientists at Karolinska Institutet in Sweden have made a large step towards the understanding of how human genes are regulated. In a new study, published in the journal Cell, they identified the DNA sequences that bind to ...

Cholera strain evolves new mechanism for causing disease

New clinical strains of cholera appear to have evolved a distinctly different mechanism to cause the same disease according to research published in the current issue of the online journal mBio.

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