As a new tool in CRISPR genome editing, Cpf1 has sparked an explosion of interest for its attributes that differ from Cas9: It requires only a single RNA that CRISPR RNA assembly is simpler; its staggered cleavage patterns ...
Biotechnology
Jun 6, 2016
0
136
The ability to edit genes in living organisms offers the opportunity to treat a plethora of inherited diseases. However, many types of gene-editing tools are unable to target critical areas of DNA, and creating such a technology ...
Cell & Microbiology
Aug 24, 2019
0
516
Skoltech scientists and their colleagues from Germany and the United States have analyzed the metabolomes of humans, chimpanzees, and macaques in muscle, kidney, and three different brain regions. The team discovered that ...
Evolution
May 24, 2021
3
263
Although cats have lived alongside humans for millennia, it remains a dogs' world. This bias has historically bled into science as well. It's time for cats to get their day, argues veterinary medicine expert Leslie Lyons ...
Biotechnology
Jul 28, 2021
3
749
Biologists at the Universities of Bath and Vienna have discovered 71 new 'imprinted' genes in the mouse genome, a finding that takes them a step closer to unraveling some of the mysteries of epigenetics—an area of science ...
Molecular & Computational biology
Jun 21, 2021
0
22
Rice University scientists have detected at least three instances of cross-species mating that likely influenced the evolutionary paths of "old world" mice, two in recent times and one in the distant past.
Biotechnology
Dec 16, 2014
0
0
Researchers at the University of Michigan Life Sciences Institute and the Howard Hughes Medical Institute have determined how satellite DNA, considered to be "junk DNA," plays a crucial role in holding the genome together.
Biotechnology
Apr 11, 2018
0
170
Are you a man or a mouse? A new paper, published in this week's issue of PLoS Biology, explores exactly what distinguishes our genome from that of the lab mouse. In the first comprehensive comparison between the genes of ...
Cell & Microbiology
May 27, 2009
0
0
Genome editing using CRISPR/Cas system has enabled direct modification of the mouse genome in fertilized mouse eggs, leading to rapid, convenient, and efficient one-step production of knockout mice without embryonic stem ...
Biotechnology
May 1, 2015
0
35
Nature vs. nurture has long been one of the great debates in science—is behavior hard-wired into the brain, or determined by environment? In at least some cases, Harvard researchers are showing, how animals behave is in ...
Plants & Animals
Jan 16, 2013
1
0
