COVID is not yet under control. Despite a bevy of vaccines, monoclonal antibodies, and antivirals, the virus continues to mutate and elude us. One solution that scientists have been exploring since the early days of the pandemic ...
Bio & Medicine
Mar 14, 2023
0
104
An MUSC Hollings Cancer Center research team has created what team members believe to be among the first small molecules designed to stimulate immune cells to fight cancer. More importantly, these compounds inhibit a specific ...
Biochemistry
Feb 28, 2023
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124
Of the 25,000 different proteins in the human body, insulin, antibodies, and collagen are among the few that perform their biological jobs by literally folding into 3D shapes.
Cell & Microbiology
Dec 5, 2022
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3
Using an approach based on CRISPR proteins, MIT researchers have developed a new way to precisely control the amount of a particular protein that is produced in mammalian cells.
Biotechnology
Nov 1, 2022
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28
Like the Roadrunner outwitting Wile E. Coyote, SARS-CoV-2 (the infectious virus responsible for COVID-19) keeps mutating, generating new variants that can slip from the grip of a well-trained immune system or a well-aimed ...
Biochemistry
Sep 9, 2022
0
119
NIST Standard Reference Material (SRM) 3655 helps biopharmaceutical manufacturers perform measurements of glycan molecules in their protein drug products, including the monoclonal antibodies (mAbs) that currently dominate ...
Other
Aug 3, 2022
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19
In a study recently published in Cell Reports Methods, co- authors Björn Önfelt, Niklas Sandström and Valentina Carannante, researchers at SciLifeLab and the Department of Microbiology, Tumor and Cell Biology at Karolinska ...
Cell & Microbiology
Jul 19, 2022
0
17
Arthritis can keep a cat from doing many of the things that kitties love to do. But now there's hope: The first treatment to ease arthritis pain in cats has been approved by the U.S. Food and Drug Administration.
Veterinary medicine
Jan 13, 2022
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7
It is widely understood that antibodies neutralize viruses by latching onto their surfaces and blocking them from infecting host cells. But new research reveals that this barrier method isn't the only way that antibodies ...
Cell & Microbiology
Nov 30, 2021
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606
Challenging the dogma of what scientists thought they understood about DNA viruses, a team of researchers led by Children's Hospital of Philadelphia (CHOP) has shown that adenovirus uses its own efficient RNA splicing mechanisms ...
Molecular & Computational biology
Oct 21, 2021
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68
Monoclonal antibodies (mAb or moAb) are monospecific antibodies that are identical because they are produced by one type of immune cell that are all clones of a single parent cell. Given almost any substance, it is possible to create monoclonal antibodies that specifically bind to that substance; they can then serve to detect or purify that substance. This has become an important tool in biochemistry, molecular biology and medicine. When used as medications, the generic drug name ends in -mab (see "Nomenclature of monoclonal antibodies").
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