Missing link explains mRNA delivery in brain cells

Brain cells manufacture proteins in every corner, including their long branches. Neurons missing this ability cause severe neurological disorders like disability and epilepsy. The groups of Marino Zerial, Max Planck Institute ...

Ibogaine inspires new compounds to treat addiction, depression

Scientists have developed two new drug candidates for potentially treating addiction and depression, modeled on the pharmacology of a traditional African psychedelic plant medicine called ibogaine. At very low doses, these ...

Structural insight into process of gene regulation

In the cell nucleus, numerous proteins bind to the DNA molecule in order to regulate the activity of certain genes. One of these is the TATA-box binding protein (TBP), which binds to a specific DNA sequence and constitutes ...

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