Related topics: type 2 diabetes

First mouse model with mitochondrial tRNALeu mutation developed

Studying the role of mitochondria—the specialized structures within cells responsible for energy production—in metabolic diseases has been difficult because of a lack of animal models with the necessary mitochondrial ...

How the body senses an essential amino acid

A new paper from Whitehead Institute researchers reveals how mice sense an essential amino acid called leucine, which many people get from eating fish, eggs, or nuts. Down the line, the work could inform research into creating ...

New tool to accelerate drug discovery

Inside your body on the surface of cell membranes, a metaphorical communication and traffic network is underway as hormones—or chemical messengers—bind to cell membrane receptors to fine tune how the cell behaves. Once ...

SRC-3 is a key regulator of the 12-hour clock

Many people have heard of the circadian rhythms or biological processes that follow a 24-hour cycle. Sleeping at night and being awake during the day is a well-known example of a circadian rhythm. Less well known are the ...

New biomarker for severe COVID-19

During the pandemic, it has become evident that people with cardiovascular disease and obesity are at much higher risk of developing very severe, even fatal COVID-19 disease. Researchers at Karolinska Institutet have identified ...

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