One of the biggest challenges in scientists' quest to develop new and better treatments for cancer is gaining a better understanding of how and why cancer spreads. Recent breakthroughs have uncovered how different cellular ...
Biochemistry
Aug 19, 2009
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In a landmark technical achievement, investigators in the Vanderbilt Center for Structural Biology have used nuclear magnetic resonance (NMR) methods to determine the structure of the largest membrane-spanning protein to ...
Cell & Microbiology
Jun 25, 2009
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Revered in India as "holy powder," the marigold-colored spice known as turmeric has been used for centuries to treat wounds, infections and other health problems. In recent years, research into the healing powers of turmeric's ...
Analytical Chemistry
Mar 6, 2009
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Many drug and antibody discovery pathways focus on intricately folded cell membrane proteins: when molecules of a drug candidate bind to these proteins, like a key going into a lock, they trigger chemical cascades that alter ...
Biotechnology
Jun 21, 2024
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A new way to study protein movements has been developed by researchers at Umeå University and the MAX IV Laboratory in Lund. The method enables significantly more experiments than before and allows us to learn more about ...
Molecular & Computational biology
Jun 18, 2024
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A bacterial enzyme called histidine kinase is a promising target for new classes of antibiotics. However, it has been difficult to develop drugs that target this enzyme, because it is a "hydrophobic" protein that loses its ...
Biotechnology
Jun 10, 2024
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17
The opportunistic bacterial pathogen Pseudomonas aeruginosa is dangerous due to its resistance to multiple antibiotics. A research team from Heinrich Heine University Düsseldorf (HHU) and Jülich Research Center (Forschungszentrum ...
Biochemistry
May 13, 2024
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21
In a study published in Proceedings of the National Academy of Sciences, Umeå researchers describe a natural product-like molecule, Tantalosin, that inhibits interaction between two proteins in complexes that reshape membranes ...
Biochemistry
May 3, 2024
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30
Pyroptosis is a type of programmed cell death mediated by the gasdermin (GSDM) protein family, which plays important roles in the body's defense against pathogen infection, elimination of abnormal or harmful cells, and other ...
Cell & Microbiology
Apr 29, 2024
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23
In a first demonstration of "electron videography," researchers have captured a microscopic moving picture of the delicate dance between proteins and lipids found in cell membranes. The technique can be used to study the ...
Bio & Medicine
Apr 22, 2024
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