It was a good year for research across multiple fields as a team at the University of Ottawa, working with colleagues Danilo Zia and Fabio Sciarrino, from the Sapienza University of Rome, demonstrated a novel technique to ...
Helicases are enzymes that unwind DNA and RNA. They're central to cellular life, implicated in a number of cancers and infections—and, alas, extraordinarily difficult to target with drugs.
Biochemistry
Mar 7, 2024
0
31
Scientists associated with the international software project MZmine, led by Dr. Robin Schmid and Dr. Tomáš Pluskal from the Institute of Organic Chemistry and Biochemistry of the Czech Academy of Sciences, have come up ...
Biochemistry
Dec 13, 2023
0
40
When Senior Scientist Jonathan Grimm came to Janelia 13 years ago, he didn't know much about fluorescence or fluorescent dyes. But as an organic chemist who had been working in drug discovery at Merck, he certainly knew a ...
Analytical Chemistry
Dec 8, 2023
0
20
Researchers at the Institute for Basic Science (IBS) in South Korea have made a groundbreaking discovery by identifying the structure and reactivity of rhodium-acylnitrenoid intermediates in catalytic hydrocarbon amination ...
Analytical Chemistry
Jul 20, 2023
0
5
Surprisingly, bitter taste receptors are not only located in the mouth, but also elsewhere in the body, including the airways. Activating those receptors opens up lung passageways, so they're a potential target for treating ...
Biochemistry
Mar 13, 2023
0
26
The evolutionary secrets that enable the medicinal herb known as barbed skullcap to produce cancer fighting compounds have been unlocked by a collaboration of UK and Chinese researchers.
Plants & Animals
Jan 19, 2023
0
87
A chemistry collaboration has led to a creative way to put carbon dioxide to good—and even healthy—use: by incorporating it, via electrosynthesis, into a series of organic molecules that are vital to pharmaceutical development.
Materials Science
Jan 5, 2023
2
664
In synthetic organic chemistry, so-called cycloadditions are a particularly important class of reactions. With this type of reaction, ring-shaped molecules can be constructed simply and efficiently by joining ("adding") two ...
Materials Science
Mar 23, 2022
0
102
The most common pharmaceuticals on the market are made by chaining together rings of molecules to create the drugs that treat conditions including pain, depression and leukemia.
Analytical Chemistry
Nov 16, 2021
0
18
