EPFL scientists have developed a ligand molecule that connects peptide drugs to blood-serum albumin and keeps them from being cleared out by the kidneys too soon. The ligand is easy to synthesize and can extend the half-life ...
Biochemistry
Jul 17, 2017
0
398
Receptors are how the body senses its environment. Upon the binding of a ligand, a receptor will initiate a chain of events that elicits a response. Our olfactory system depends on approximately 400 receptors to give us our ...
Biochemistry
Jun 8, 2017
0
4
Metal complexes bearing N-heterocyclic carbene ligands (NHC ligands) have been successfully used in a number of catalytic reactions. High stability of metal-NHC complexes and convenient synthesis of well-defined catalyst ...
Materials Science
Jun 8, 2017
0
3
To treat headaches, back pain or fever, most of us have reached for ibuprofen at one point or another. But we often have to take doses every four to six hours if the pain warrants it. Now scientists are working on a way to ...
Biochemistry
Apr 26, 2017
0
25
A new strategy for ligand design may enable challenging metal-catalyzed cross couplings reactions that are indispensable to drug development, according to a study published in Nature Chemistry. Based on subtle differences ...
Materials Science
Mar 27, 2017
0
86
Researchers at The University of Manchester have entered the "Wild West" of the periodic table to finally solve a decades-old scientific challenge—and have revealed that an important but niche chemical bonding principle ...
Materials Science
Feb 13, 2017
0
23
A combined theoretical and experimental approach has allowed researchers to predict and verify the full structure of a monolayer-coated molecular metal nanoparticle. The methodology was tested on silver-thiolate nanoparticles, ...
Nanomaterials
Nov 29, 2016
0
871
Scientists at The Scripps Research Institute (TSRI) have developed a powerful new method for finding drug candidates that bind to specific proteins.
Biochemistry
Jun 15, 2016
0
10
Perovskite materials have shown great promise for use in next-generation solar cells, light-emitting devices (LEDs), sensors, and other applications, but their instability remains a critical limitation.
Materials Science
Jun 13, 2016
0
126
(Phys.org)—A team of researchers working at Philipps-Universität Marburg, in Germany has created a new kind of material that is able to convert a near-infrared laser beam into a visible beam of light. In their paper published ...
