Researchers establish crystal structure of gastric proton pump

The highly acidic environment in the stomach is essential for digestion. Furthermore, it acts as an important barrier to invasive pathogens. However, excessive stomach acidification leads to ulcers. Although this is not a ...

An improved anti-addiction medication

Drug addiction continues to plague vast numbers of people across the world, destroying and ending lives, while attempts to develop more effective pharmaceutical addiction treatments continue. Scientists now report in the ...

Rooting out doping in racehorses

Doping in the horseracing industry has spurred regulations banning performance-enhancing drugs, as well as calls for an anti-doping agency in the U.S. But as in human sports, testing for certain kinds of prohibited substances ...

Fish exposed to SSRIs exhibit abnormal behavior, study finds

Fish exhibit abnormal behavior and lower levels of anxiety when exposed to Selective Serotonin Reuptake Inhibitors (SSRI), which are common drugs used to treat depression, among other disorders. The study, by Baylor University ...

Immunoproteasome crystal structure determined

Like a shredder, the immunoproteasome cuts down proteins into peptides that are subsequently presented on the cellular surface. The immune system can distinguish between self and nonself peptides and selectively kills cells ...

A powerful new technology to identify HIV inhibitors

Providing long-term HIV treatment for over 33 million infected individuals worldwide requires the continuous development of new HIV therapies. Virologists at the Helmholtz Zentrum Munchen have developed a cell-based assay ...

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