In a technical tour de force, scientists at Fox Chase Cancer Center have cataloged and cross-indexed the actions of 178 candidate drugs capable of blocking the activity of one or more of 300 enzymes, including enzymes critical ...
Biotechnology
Oct 30, 2011
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A new study suggests that combining two experimental anticancer peptide agents might simultaneously block formation of new tumor blood vessels while also inhibiting the growth of tumor cells.
Biochemistry
Mar 14, 2011
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An innovative drug-delivery system - nanoparticles encapsulating nitric oxide or prescription drugs - shows promise for topical treatment of erectile dysfunction (ED), according to a new study by scientists at Albert Einstein ...
Bio & Medicine
Sep 19, 2009
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A research team led by U of T Mississauga scientists has developed a new way to split up a dangerous pair of cancer proteins, a finding that could ultimately lead to chemotherapy that is more effective and has fewer side ...
Biochemistry
Aug 20, 2009
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Chronic pain is an extremely common condition that affects about 20% of the general population. Given the shortage of effective and non-addictive analgesics, new anti-pain drugs are eagerly awaited. Voltage-gated sodium channel ...
Molecular & Computational biology
Nov 28, 2022
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2
In the search for treatments for COVID-19, many researchers are focusing their attention on a specific protein that allows the virus to infect human cells. This protein, which cells carry on their surface, is called angiotensin ...
Cell & Microbiology
May 5, 2021
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13
Scientists at Harvard Medical School and the Dana-Farber Cancer Institute have developed a method that exploits the multitargeted nature of a chemical inhibitor to pinpoint vulnerabilities within cancer cells.
Biochemistry
Apr 4, 2019
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7
A team of researchers from the Singapore University of Technology and Design (SUTD) and Nanyang Technological University (NTU) have developed novel ferrocene-based molecules that impair the malaria parasite's metabolic function ...
Biochemistry
Dec 20, 2018
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7
Linking therapeutically active molecules to specific antibodies can help to pilot them to their designated targets and minimize side effects—especially when treating tumors. In the journal Angewandte Chemie, scientists ...
Biochemistry
Oct 30, 2018
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7
A new study reveals that several drugs for treating haematological cancers are less effective than expected in inhibiting a special enzyme. Researchers have also identified new lead compounds that could potentially improve ...
Biochemistry
Jul 26, 2018
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