Scientists at the University of Virginia School of Medicine have developed a tool to monitor communications within the brain in a way never before possible, and it has already offered an explanation for why Alzheimer's drugs ...
Bio & Medicine
Mar 9, 2021
0
69
PARP inhibitors are recently developed drugs that have shown great promise against some types of ovarian, breast, prostate and pancreatic cancer, but many patients' tumors develop resistance to the drugs. Now researchers ...
Cell & Microbiology
Jan 19, 2021
0
24
Researchers at the University of Copenhagen have used highly sophisticated molecular analyses to identify key proteins in the signaling pathways that cancers use to spread in the body. The study could help in personalizing ...
Cell & Microbiology
Oct 4, 2019
0
45
Researchers investigating ways to deliver high doses of cancer-killing drugs inside tumors have shown they can use a laser and light-activated gold nanoparticles to remotely trigger the release of approved cancer drugs inside ...
Bio & Medicine
Nov 8, 2017
0
157
The term "synergy" has gained a reputation as an overused buzzword, but it has a quantifiable definition in pharmacology. Two drugs are considered synergistic when their effectiveness when used together is greater than the ...
Biochemistry
Oct 2, 2017
0
76
Cancer cells are more dependent on a cellular garbage disposal unit—the proteasome—than healthy cells, and cancer therapies take advantage of this dependency. Scientists at EMBL and MPI determined the proteasome's 3D ...
Biochemistry
Aug 4, 2016
0
872
Scientists have made a major breakthrough in the global search for a new drug to beat the malaria parasite's growing resistance to first-defence treatments.
Biochemistry
Feb 10, 2016
0
34
Protease inhibitors are a class of antiviral drugs that are commonly used to treat HIV, the virus that causes AIDS. Scientists at the University of Nebraska Medical Center designed a new delivery system for these drugs that, ...
Bio & Medicine
Oct 19, 2015
2
106
(Phys.org)—Research led by the University of Bath has identified two possible new routes for developing novel drugs for high blood pressure and heart disease.
Biochemistry
Oct 10, 2012
0
0
(PhysOrg.com) -- A team of researchers at Karolinska Institutet in Sweden has generated a map over the effects of small drug-like molecules on PARP1 and other similar proteins in the body. This map may explain the mechanism ...
Biotechnology
Feb 20, 2012
0
0
