Research led by Sichuan University and Huazhong University of Science and Technology, China, has revealed genetic mechanisms that could prolong healthy aging. In the paper, titled "Partial inhibition of class III PI3K VPS-34 ...
Scientists from The Scripps Research Institute have identified a class of compounds that could be a boon to basic research and drug discovery.
Biochemistry
May 15, 2011
1
0
Male fruit flies don't usually like each other. Socially, they reject their fellow males and zero in on the females they discern via chemical receptors—or so scientists thought.
Plants & Animals
Sep 5, 2023
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60
The p38 protein regulates a wide variety of cellular functions and is related to diseases such as chronic inflammation, immunological disorders, or cancer. To date, it has been difficult to find p38 inhibitors for use in ...
Biotechnology
Jul 13, 2023
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1
Neurons are constantly performing complex calculations to process sensory information and infer the state of the environment. For example, to localize a sound or to recognize the direction of visual motion, individual neurons ...
Molecular & Computational biology
Feb 23, 2022
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887
Researchers at McGill University have invented a new technique for measuring how quickly drugs interact with their molecular targets. The discovery provides scientists with a new way to investigate the effectiveness of drug ...
Biochemistry
Mar 1, 2018
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100
After mating for the first time, most females of an Australian jumping spider are unreceptive to courtship by other males, and this sexual inhibition is immediate and often lasts for the rest of their lives, according to ...
Plants & Animals
Oct 18, 2017
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86
Many American parents yell or shout at their teenagers. A new longitudinal study has found that using such harsh verbal discipline in early adolescence can be harmful to teens later. Instead of minimizing teens' problematic ...
Social Sciences
Sep 4, 2013
9
2
A family of nutrient-sensing enzymes, dubbed Rag GTPases, modulates the activity of the mTORC1 protein complex, whose inhibition is essential for autophagy and survival in newborn mammals. One enzyme, RagA, has been found ...
Cell & Microbiology
Dec 23, 2012
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0
(Phys.org)—How does one define the factors on the surface of human cells to which a molecule of interest binds? This question is typically hard to answer. Researchers of ETH Zurich have developed a new technology that enables ...
Biotechnology
Oct 5, 2012
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