New tool could help researchers design better cancer vaccines
A computational model could improve the selection of tumor antigens for personalized cancer vaccines that are now in early-stage clinical trials.
A computational model could improve the selection of tumor antigens for personalized cancer vaccines that are now in early-stage clinical trials.
Biotechnology
Dec 17, 2019
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20
Glycosylation—the attachment of sugars to proteins—plays a critical role in both cellular function and in the development of therapeutics, like vaccines.
Cell & Microbiology
Nov 27, 2019
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57
In a paper published in Cell Reports, a team of researchers from the Department of Energy's SLAC National Accelerator Laboratory and Stanford University discovered unique characteristics of a protein called VISTA that protects ...
Biochemistry
Nov 18, 2019
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154
Tiny vehicles up to 1,000 times smaller than the width of a human hair that are cloaked in biological camouflage could provide new ways of treating cancer with fewer side-effects.
Bio & Medicine
Nov 5, 2019
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9
Vaccines made from RNA hold great potential as a way to treat cancer or prevent a variety of infectious diseases. Many biotech companies are now working on such vaccines, and a few have gone into clinical trials.
Biotechnology
Sep 30, 2019
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132
Diversity is good, especially when it comes to antibodies. It's long been known that a gene assembly process called V(D)J recombination allows our immune system to mix and match bits of genetic code, generating new antibodies ...
Cell & Microbiology
Sep 13, 2019
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59
The same genetic mutations that can trigger cancer in some tissues are relatively harmless in others. A new Yale study has identified an unlikely source of protection against some forms of skin cancer—hair follicle regeneration.
Cell & Microbiology
Sep 6, 2019
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5
Dr. Mihue Jang and her group at the Center for Theragnosis of the Korea Institute of Science and Technology (KIST, President Byung-gwon Lee) announced that they have developed a new gene editing system that could be used ...
Bio & Medicine
Aug 20, 2019
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13
Researchers at Tel Aviv University have developed a novel nano-vaccine for melanoma, the most aggressive type of skin cancer. Their innovative approach has so far proven effective in preventing the development of melanoma ...
Bio & Medicine
Aug 5, 2019
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794
One of the greatest enigmas of evolutionary biology is that while sex is the dominant mode of reproduction among multicellular organisms, asexual reproduction appears much more efficient and less costly. However, in a study ...
Evolution
Jun 6, 2019
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358