Researchers at Karolinska Institutet and Stockholm University have developed a new technology allowing simultaneous probing of several different histone marks in one individual cell and in thousands of cells at the same time. ...
Cell & Microbiology
Dec 20, 2022
0
55
If you stretched the DNA found in one of your cells from end to end, it would extend approximately 2 meters or 6.5 feet. Every single cell in your body can pack away this much DNA by winding it around proteins called histones. ...
Biochemistry
Dec 19, 2022
0
157
Researchers from the Gerlich Group at IMBA—Institute of Molecular Biotechnology of the Austrian Academy of Sciences—discovered a molecular mechanism that confers special physical properties to chromosomes in dividing ...
Molecular & Computational biology
Aug 3, 2022
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73
If you are moaning once again about your suitcase being far too small as your vacation approaches, you should take human sperm cells as an inspiration. During their production, they are faced with an almost insoluble task. ...
Cell & Microbiology
Jul 11, 2022
0
65
In almost every human cell, 2 meters of DNA has to fit within a nucleus that is just 8 millionths of a meter wide. Like wool around a spool, the extreme space challenge requires DNA to wrap around structural proteins called ...
Evolution
Jun 9, 2022
0
47
To keep order in the tight quarters of the cell nucleus, our DNA is neatly clamped in place around a central disk by H1 linker histone, which helps shepherd DNA into the tidy chromatin fibers that comprise chromosomes. Linker ...
Molecular & Computational biology
May 27, 2022
0
40
New research from Royal Holloway has discovered how natural responses to stress in plants modify the way DNA is wrapped up in the cell to help it withstand the adverse effects that climate change has on its growth.
Molecular & Computational biology
Apr 11, 2022
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117
A new Cornell study, published in Nature Genetics, sheds light on a controversial debate in epigenetics—the set of molecular changes occurring on top of the genome that regulate how genes are turned on and off, but without ...
Biotechnology
Mar 14, 2022
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18
Researchers have developed a technique that allows them to look simultaneously at a spatial level and at a genome-wide level at epigenetic mechanisms underlying tissue development, a breakthrough with multiple scientific ...
Biotechnology
Feb 11, 2022
0
109
Immunologists at St. Jude Children's Research Hospital have identified biochemical "switches" that control development of regulatory T cells and offer a novel strategy for treatment of autoimmune diseases and cancer. The ...
Cell & Microbiology
Dec 29, 2021
0
287
