Glycosylation is the attachment of carbohydrates to the backbone of a protein through an enzymatic reaction. It plays a critical role in determining protein structure, function and stability. A protein that is glycosylated ...
Biochemistry
Sep 27, 2023
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1
Protein glycosylation is one of the most important post-translational modifications that can be exploited to improve various aspects of therapeutic proteins and industrial enzymes. Different types of glycosylation have a ...
Molecular & Computational biology
Sep 8, 2023
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1
Glycans perform varied and crucial functions in numerous cellular activities. The diverse roles of glycans are matched by their highly complex structures, which derive from differences in composition, branching, regio- and ...
Biochemistry
May 8, 2023
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87
A research study has shed new light on how congenital muscular dystrophies such as Walker-Warburg syndrome progress, bringing hope for better understanding, early diagnosis and treatments of these fatal disorders.
Molecular & Computational biology
Mar 10, 2023
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233
Coronaviruses, such as the one that causes COVID-19, have numerous protruding spikes salting their surfaces. When a coronavirus raises one of these spike proteins—like opening a finger to full length—it becomes capable ...
Molecular & Computational biology
Jan 20, 2023
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54
MIT researchers have identified molecules found in mucus that can block cholera infection by interfering with the genes that cause the microbe to switch into a harmful state.
Molecular & Computational biology
Dec 12, 2022
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128
Many proteins contain patterns of sugar molecules (glycans) and are made of several aggregated subunits. This glycosylation and oligomerization has a decisive influence on protein function and must be considered in biopharmaceutical ...
Biochemistry
Nov 14, 2022
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21
If you're an avid reader of science news, you've probably heard of viral proteins such as the COVID-19 spike protein.
Biochemistry
Sep 26, 2022
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66
Bacteria in our bodies bind to various host cell surface receptors, which determines where the bacteria live and how they behave. These receptors, made up of chains of sugar molecules called glycans, are more than meets the ...
Biochemistry
Aug 17, 2022
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26
NIST Standard Reference Material (SRM) 3655 helps biopharmaceutical manufacturers perform measurements of glycan molecules in their protein drug products, including the monoclonal antibodies (mAbs) that currently dominate ...
Other
Aug 3, 2022
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19
