Further insights into the SARS-CoV-2 spike protein glycan shield

An unprecedented wealth of information has been gathered on SARS-CoV-2 in a very short period. This information is primarily focused on the cellular entry process and mechanism of antibody recognition where mainly protein-protein ...

Neutralizing the SARS-CoV-2 sugar coat

Researchers have identified two sugar-binding proteins that impede the viral entry of circulating SARS-CoV-2 variants. The team, spearheaded by researchers at IMBA—Institute of Molecular Biotechnology of the Austrian Academy ...

A winning combination for glycoprotein synthesis

Many processes in the body are regulated by the functions of proteins. For example, almost all molecules—such as DNA, proteins, oligosaccharides, and small bioactive molecules—are generated by enzymes. However, changes ...

AI model examines virus spread from animals to humans

A new model that applies artificial intelligence to carbohydrates improves the understanding of the infection process and could help predict which viruses are likely to spread from animals to humans. This is reported in a ...

Glycans are crucial in COVID-19 infection

A research group at the RIKEN Center for Computational Science (R-CCS) has found that glycans—sugar molecules—play an important role in the structural changes that take place when the virus which causes COVID-19 invades ...

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