Artificial intelligence folds RNA molecules

For the function of many biomolecules, their three-dimensional structure is crucial. Researchers are therefore not only interested in the sequence of the individual building blocks of biomolecules, but also in their spatial ...

New technology helps reveal inner workings of human genome

Weill Cornell Medicine and New York Genome Center researchers, in collaboration with Oxford Nanopore Technologies, have developed a new method to assess on a large scale the three-dimensional structure of the human genome, ...

Effect of small polyanions on retroviruses

A retrovirus is a virus that inserts a copy of its genome into the DNA of a host cell that it invades, thus changing that cell's genome. Once inside the host cell's cytoplasm, the virus uses its reverse transcriptase enzyme ...

Decoding human history with ancient DNA

This year is the 20th anniversary of sequencing the human genome. In honor of this event, a research team led by Prof. FU Qiaomei from the Institute of Vertebrate Paleontology and Paleoanthropology (IVPP) of the Chinese Academy ...

Untwisting DNA reveals new force that shapes genomes

Advances in microscopy have enabled researchers to picture loops of DNA strands for the first time. The images reveal how the human genome organizes itself in three-dimensional space at much higher resolution than previously ...

How to tame a restless genome

Short pieces of DNA—jumping genes—can bounce from one place to another in our genomes. When too many DNA fragments move around, cancer, infertility, and other problems can arise. Cold Spring Harbor Laboratory (CSHL) Professor ...

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