A research team from the Center for Translational Stem Cell Biology (CTSCB) under the LKS Faculty of Medicine at the University of Hong Kong (HKUMed) has developed the world's first cellular system that can be used to rapidly ...
Cell & Microbiology
Jun 27, 2024
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0
An international research team has discovered that a previously overlooked repetitive DNA element known as Long Interspersed Nuclear Element (L1) helps maintain neural progenitor cells, and thus plays an important role in ...
Cell & Microbiology
Feb 14, 2024
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29
A recent Northwestern Medicine study published in the Journal of Cell Biology has identified new mechanisms that cause genomic or chromosomal instability during cell division, findings that may improve the development of ...
Cell & Microbiology
Jun 13, 2023
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13
A research team led by Dr. Gary Ying Wai Chan from the School of Biological Sciences at The University of Hong Kong (HKU), has revealed the function of a unique enzyme, ANKLE1. ANKLE1 acts on chromatin bridges that are trapped ...
Cell & Microbiology
Apr 18, 2023
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370
CRISPR/Cas9 is a precise gene editing technique whose development by Jennifer A. Doudna and Emmanuelle Charpentier was recognized with the 2020 Nobel Prize in Chemistry. Commonly known as "genetic scissors," CRISPR allows ...
Biotechnology
Aug 9, 2022
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3005
Chromosomes undergo precise structural changes at a molecular level during the different phases of cell division. These changes occur at a high level of accuracy to prevent genome instability. Genome instability resulting ...
Cell & Microbiology
May 27, 2022
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24
There are many ways in which the genetic material DNA can be damaged, resulting in the development of diseases such as cancer. Certain forms of DNA damage are associated with so-called R-loops. These are three-stranded structures ...
Molecular & Computational biology
Feb 8, 2022
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21
Cancer is a devastating disease and is the second leading cause of death in the U.S. One of the hallmarks of cancer is genomic instability, or the tendency to accumulate mutations and damage to the DNA that leads to genome ...
Cell & Microbiology
Sep 23, 2021
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13
DNA replication is essential for living organisms to faithfully deliver genetic information from parental cells to daughter cells. Many proteins are assembled on the parental DNA to work as replication machineries. Among ...
Biotechnology
Jun 3, 2019
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11
New published research from the College of Veterinary Medicine shows that heightened levels of genomic instability can prove fatal to female embryos in mice.
Biotechnology
Feb 21, 2019
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