Related topics: genome · protein · cells · mutations · gene expression

CRISPRlnc: New lncRNA-specific SgRNA design method proposed

Long non-coding RNAs (lncRNAs) are non-protein-coding transcripts. Currently, CRISPR/Cas9 is a promising RNA-guided genome editing technology consisting of a Cas9 nuclease and a single-guide RNA (sgRNA). Considering the significant ...

Revealing the evolutionary origin of genomic imprinting 

Some of our genes can be expressed or silenced depending on whether we inherited them from our mother or our father. The mechanism behind this phenomenon, known as genomic imprinting, is determined by DNA modifications during ...

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