Recent studies have suggested a potential barrier to making CRISPR gene-editing treatments a viable option for inherited blood-related disorders such as sickle cell anemia, thalassemia, and primary immunodeficiency syndromes. ...
Biotechnology
Mar 21, 2019
0
100
Scientists have developed a method to boost the efficiency of CRISPR gene editing in Duchenne muscular dystrophy (DMD), according to a study that could have implications for optimizing gene therapies for other diseases.
Biotechnology
Mar 6, 2019
0
581
Scientists from ITMO in collaboration with international colleagues have proposed new DNA-based nanomachines that can be used for gene therapy for cancer. This new invention can greatly contribute to more effective and selective ...
Bio & Medicine
Feb 8, 2019
0
369
Within a few years, Jim Johnsen and Delaney Van Riper may be among the first to benefit from CRISPR-Cas9 gene editing, a breakthrough that has already revolutionized biology research and promises to resurrect gene therapy.
Biotechnology
Oct 26, 2018
2
642
Delivering functional genes into cells to replace mutated genes, an approach known as gene therapy, holds potential for treating many types of diseases. The earliest efforts to deliver genes to diseased cells focused on DNA, ...
Biochemistry
Oct 16, 2018
0
71
The imaging method called cryo-electron microscopy (cryo-EM) allows researchers to visualize the shapes of biological molecules with an unprecedented level of detail. Now, a team led by researchers from the Salk Institute ...
Biochemistry
Sep 7, 2018
0
42
Scientists at the Wellcome Sanger Institute have discovered that CRISPR/Cas9 gene editing can cause greater genetic damage in cells than was previously thought. These results create safety implications for gene therapies ...
Biotechnology
Jul 16, 2018
0
107
With targeted drug and gene therapies, finding the target cells is only half the battle. Once these agents reach a cell's surface, they still have to get inside and do their job.
Bio & Medicine
May 22, 2018
0
21
Biomedical engineers at Duke University have used a CRISPR/Cas9 genetic engineering technique to turn off a gene that regulates cholesterol levels in adult mice, leading to reduced blood cholesterol levels and gene repression ...
Biotechnology
Apr 26, 2018
0
410
Delivering medications safely and accurately is of great interest to researchers and, of course, to people who need them. So is restoring function to damaged body parts. Jin K. Montclare, an associate professor of chemical ...
Polymers
Apr 16, 2018
0
21
