CRISPR method for conditional gene regulation

A team of engineers at the University of Delaware has developed a method to use CRISPR/Cas9 technology to set off a cascade of activities in cells, a phenomenon known as conditional gene regulation. Their method, described ...

What gave us the advantage over extinct types of humans?

In parallel with modern man (Homo sapiens), there were other, extinct types of humans with whom we lived side by side, such as Neanderthals and the recently discovered Denisovans of Siberia. Yet only Homo sapiens survived. ...

Hibernation slows biological aging in bats

The most common bat in the United States, the big brown bat, boasts an unusually long lifespan of up to 19 years. A new study led by University of Maryland researchers identifies one of the secrets to this bat's exceptional ...

Research shows microplastics are damaging to coral ecosystems

Microplastics are a growing environmental concern, and the effects of this waste product on coral are highlighted in research published in Chemosphere from an international team of researchers including UConn marine science ...

New details about gene regulation explained

(Phys.org) -- When genetic information is read from the genetic blueprint DNA, RNA polymerase II translates it into RNA molecules. The C-terminal domain, abbreviated as CTD, is an important area of the polymerase molecule. ...

CRISPR meets single-cell sequencing in new screening method

Genome editing using CRISPR/Cas9 "gene scissors" is a powerful tool for biological discovery and for identifying novel drug targets. In pooled CRISPR screens, a large number of cells are edited simultaneously using CRISPR ...

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