Enhancer RNAs may open new avenues for gene therapy

A study investigating the function of the recently discovered enhancer RNA molecules may open new avenues for gene therapy. According to the study researchers, altering the production and function of these molecules could ...

Genomic and computational tools provide window to distant past

Out of the estimated 23,000 or more genes in the human genome, about 100 of them will differ—they will be present or not—between any two individuals. Genes lost or gained over time result from evolution and adaptation, ...

Decoding mystery sequences involved in gene regulation

Every cell in an organism's body has the same copy of DNA, yet different cells do different things; for example, some function as brain cells, while others form muscle tissue. How can the same DNA make different things happen? ...

The TALE of new tools to study gene regulation

In nearly every organism's genome, scattered between genes that encode proteins, long regulatory regions stretch across expanses of DNA. Understanding what role these so-called enhancer regions play in controlling the activation ...

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