The targeted treatment of pan-cancer by messenger RNA (mRNA) vaccine is a hot topic in drug research. A key challenge in mRNA design is the construction of delivery systems called lipid nanoparticles (LNPs), which serve as ...
Bio & Medicine
Jun 12, 2024
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0
Scientists at La Jolla Institute for Immunology (LJI) have developed a new computational method for linking molecular marks on our DNA to gene activity. Their work may help researchers connect genes to the molecular "switches" ...
Biotechnology
Jun 3, 2024
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231
Traits are often lost during evolution, either because they are no longer beneficial or because they are too costly to maintain. When this happens, it is generally believed that the genes underlying the trait will eventually ...
Evolution
May 29, 2024
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36
A study has tapped into the peach genome, creating large-scale gene co-expression networks (GCNs) that predict gene functions and streamline the peach breeding process. This innovative approach addresses the complex task ...
Molecular & Computational biology
May 20, 2024
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12
Many organisms are far more complex than just a single species. Humans, for example, are full of a variety of microbes. Some creatures have even more special connections, though.
Ecology
May 16, 2024
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18
The Human Genome Project generated the first sequence of the human genome, revealing a kind of blueprint of human biology. Two decades later, the field of gene regulatory networks describes a complex system where thousands ...
Biotechnology
Mar 14, 2024
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37
Gene regulatory networks (GRNs) depict the regulatory mechanisms of genes within cellular systems as a network, offering vital insights for understanding cell processes and molecular interactions that determine cellular phenotypes. ...
Molecular & Computational biology
Feb 23, 2024
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18
Over the last 20 years, researchers in biology and medicine have created Boolean network models to simulate complex systems and find solutions, including new treatments for colorectal cancer.
Molecular & Computational biology
Jan 23, 2024
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23
A team of researchers around Berlin mathematics professor Michael Joswig is presenting a novel concept for the mathematical modeling of genetic interactions in biological systems. Collaborating with biologists from ETH Zurich ...
Molecular & Computational biology
Dec 18, 2023
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118
Single-cell multi-omics technologies allow a profound system-level biology understanding of cells and tissues. However, an integrative and possibly systems-based analysis capturing the different modalities is challenging. ...
Cell & Microbiology
Nov 28, 2023
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