Scientists find longevity biomarkers

An international group of scientists studied the effects of 17 lifespan-extending interventions on gene activity in mice and discovered genetic biomarkers of longevity. The results of their study were published in the journal ...

Location is everything for plant cell differentiation

While the fate of most human cells is determined by their lineage—for example, renal stem cells go on to form the kidney while cardiac progenitor cells form the heart—plant cells are a little more flexible. Research shows ...

Single-cell RNA profiling

An LMU team has improved both the sensitivity and efficiency of a popular method for single-cell RNA sequencing, which yields a molecular fingerprint for individual cells based on their patterns of gene activity.

Programming synthetic molecular codes to turn genes 'on'

A team of researchers in Japan developed a synthetic molecular code to script gene activation. The process, described in the Journal of the American Chemical Society, could lead to future gene-based therapies for a wide array ...

Risk-free gene reactivation

Chemical modification of DNA subunits contribute to the regulation of gene expression. Researchers from Ludwig-Maximilians-Universitaet (LMU) in Munich have now deciphered a new pathway can reactivate genes that have been ...

Matchmaking with consequences

Most human tumours have one thing in common: They harbour drastically increased amounts of the so-called Myc proteins. Animal experiments show that such high Myc concentrations contribute to causing cancer. But Myc proteins ...

How cells hack their own genes

DNA in all organisms from yeast to humans encodes the genes that make it possible to live and reproduce. But these beneficial genes make up only 2 percent of our DNA. In fact, more than two-thirds of our genome is populated ...

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